Recombinant Proteins

Recombinant Proteins

ProQinase offers a broad panel of recombinant proteins for kinase activity assays. In addition to active kinase enzymes including lipid kinases and protein kinases, we offer kinase protein variants and kinase substrates. Custom-tailored recombinant protein expression can be performed according to your specific requirements of active kinases and other potential drug targets.

Our recombinant proteins can be purchased as aliquots off-the-shelf or in bulk quantities.

 

Recombinant protein kinases can be used for the identification and characterization of kinase inhibitors. ProQinase offers a large panel of active recombinant protein kinases, immediately available off the shelf.

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Active Lipid Kinases are available from ProQinase completing our portfolio of recombinant kinases. The lipid kinases have passed ProQinase’s quality control and have been tested for activity in the non-radioactive ADP-Glo™ assay from Promega.

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In addition to active recombinant kinases, inactive or non activated protein kinases are available. These protein kinase variants have also passed ProQinase’s quality control and proofed to be inactive in kinase assays in comparison to their active counterparts.

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All kinase substrates can be used in a broad spectrum of biochemical kinase assay technologies including radiometric activity assays (e.g. FlashPlateTM, filter binding assays), in ATP consumption or antibody-based assays. Substrates have been validated for the use in radiometric assays as well as with the ADP-GloTM kinase assay technology from Promega Corp.

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If the kinase of your interest is not yet available as off-the-shelf product, we may produce this protein for you according to your specific requirements.

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