Biochemical Assay Services

Free Choice Kinase Assay Projects / Kinase Assays

Field of Application

Free choice kinase assay projects allow characterization of your test compounds in a total flexible mode. For each project you can freely define (i) the number of kinase assays, (ii) the number of test compounds (iii) and the number of data points for each test compound (i.e. number of concentrations and replicates). All kinase assays are designed to measure biochemical kinase activity.

Our Services

Number Kinase Synonyms
1 ABL1 ABL1, ABL, JTK7, p150, c-ABL, v-abl, ABL1 wt
2 ABL1 E255K ABL1, c-Abl, JTK7, p150
3 ABL1 F317I ABL1, ABL, JTK7, p150, c-ABL, v-abl
4 ABL1 G250E ABL1, ABL, JTK7, p150, c-ABL, v-abl
5 ABL1 H396P ABL1, ABL, JTK7, p150, c-ABL, v-abl
6 ABL1 M351T ABL1, ABL, JTK7, p150, c-ABL, v-abl
7 ABL1 Q252H ABL1, ABL, JTK7, p150, c-ABL, v-abl
8 ABL1 T315I ABL1, ABL, JTK7, p150, c-ABL, v-abl
9 ABL1 Y253F ABL1, ABL, JTK7, p150, c-ABL, v-abl
10 ABL2 ABL2, ABLL, ARG
11 ACK1 TNK2, ACK, p21cdc42Hs, Activated CDC42 kinase 1
12 ACVR1 ACVR1, ACTRI, ACVRLK2, ALK2, SKR1, ACV-R1
13 ACVR1B ACVR1B, ACTRIB, ACVRLK4, ALK4, SKR2, ACV-R1B
14 ACVR2A ACVR2, ACTRII, ACV-R2A
15 ACVR2B ActR-IIB, ACTRIIB, ACV-R2B
16 ACVRL1 ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, ACV-RL1
17 AKT1 AKT1, PKB, RAC, PRKBA, RAC-ALPHA, AKT1 aa1-480
18 AKT1 aa106-480 AKT1, PKB, RAC, PRKBA, RAC-ALPHA
19 AKT2 AKT2, PKBB, PKBBETA, PKB beta, PRKBB, RAC-beta, RAC-PK-beta, AKT2 aa1-481
20 AKT2 aa107-481 AKT2, PKBB, PKBBETA, PKB beta, PRKBB, RAC-beta, RAC-PK-beta
21 AKT3 AKT3, PKBG, PKB gamma, PRKBG, RAC-gamma, RAC-PK-gamma, STK-2, DKFZp434N0250, AKT3 aa1-479
22 AKT3 aa106-479 AKT3, PKBG, PRKBG, STK-2, RAC-gamma, RAC-PK-gamma
23 ALK ALK, CD246, NBLST3, ALK wt (GST-HIS-tag)
24 ALK C1156Y ALK, CD246, NBLST3, ALK C1156Y (GST-HIS-tag)
25 ALK F1174L ALK, CD246, NBLST3, ALK F1174L (GST-HIS-tag)
26 ALK F1174S ALK, CD246, NBLST3, ALK F1174S (GST-HIS-tag)
27 ALK G1202R ALK, CD246, NBLST3, ALK G1202R (GST-HIS-tag)
28 ALK L1196M ALK, CD246, NBLST3, ALK L1196M (GST-HIS-tag)
29 ALK R1275Q ALK, CD246, NBLST3, ALK R1275Q (GST-HIS-tag)
30 AMPKalpha1 PRKAA1, MGC33776, MGC57364, AMPK-alpha1 aa1-550
31 AMPKalpha1 aa1-312 PRKAA1, MGC33776, MGC57364, AMPK-alpha1 aa1-312
32 ARK5 NUAK1, KIAA0537
33 ASK1 MAP3K5, ASK1, MAPKKK5, MEKK5
34 AuroraA AURKA, AIK, ARK1, AURA, BTAK, STK15, MGC34538, STK6, Aurora-A
35 AuroraB AURKB, AIK2, AIM1, ARK2, AurB, IPL1, STK5, AIM-1, STK12, Aurora-B
36 AuroraC AURKC, AIE2, AIK3, STK13, Aurora-C
37 AXL AXL, EC, UFO
38 BLK BLK, n/a
39 BMPR1A BMPR1A, SKR5, CD292, ALK3, ACVRLK3
40 BMPR1B BMPR1B, ALK6, CDw293
41 BMX BMX, ETK, PSCTK2, PSCTK3
42 BRAF BRAF, B-Raf, B-raf-1, BRAF1, RAFB1, B-RAF wt
43 BRAF V600E BRAF, B-Raf, B-raf-1, BRAF1, RAFB1, B-RAF V600E
44 BRK PTK6, n/a
45 BRSK1 BRSK1, KIAA1811
46 BRSK2 C11orf7, FLJ41362, HUSSY-12, PEN11B, SAD1, STK29
47 BTK BTK, AGMX1, AT, ATK, BPK, PSCTK1
48 BUB1B BUB1B, BUBR1, Bub1A, MAD3L, hBUBR1
49 CAMK1D CAMK1D, CKLiK, CaM-K1, CaMKID
50 CAMK2A CAMK2A, CAMKA, KIAA0968
51 CAMK2B CAMK2B, CAM2, CAMK2, CAMKB, MGC29528
52 CAMK2D CAMK2D, CAMKD, MGC44911, CaMKII delta
53 CAMK2G CAMK2G, CAMK, CAMK-II, CAMKG, MGC26678
54 CAMK4 CAMK4, CaMK-GR, MGC36771
55 CAMKK1 CAMKK1, CAMKKA, DKFZp761M0423, MGC34095
56 CAMKK2 CAMKK2, CAMKK, CAMKKB, KIAA0787, MGC15254
57 CCDC6 RET CCDC6-RET, CCDC6-RETa, CCDC6-RET
58 CDC42BPA CDC42BPA, MRCK-alpha
59 CDC42BPB CDC42BPB, MRCK-beta, MRCKb
60 CDC7/DBF4 CDC7, CDC7L1, HsCdc7, HsCDC7, Hsk1, huCdc7
61 CDK1/CycA2 CDC2, p34
62 CDK1/CycB1 CDC2, p34
63 CDK1/CycE1 CDC2, p34
64 CDK12 R722C/CycK CDK12, CRKRS, CRK7
65 CDK12/CycK CDK12, CRKRS, CRK7, CDK12 wt/CycK
66 CDK13/CycK CDK13, CDC2L, CDC2L5, CHED
67 CDK16/CycY CDK16, PCTAIRE1, PCTAIRE, PCTGAIRE, PCTK1
68 CDK17/p35NCK CDK17, PCTAIRE2, PCTK2
69 CDK18/CycY CDK18, PCTAIRE, PCTAIRE3, PCTK3
70 CDK19/CycC CDK19, CDC2L6, CDK11
71 CDK2/CycA2 CDK2, p33(CDK2)
72 CDK2/CycD1 CDK2, p33
73 CDK2/CycE1 CDK2, p33(CDK2)
74 CDK20/CycH CDK20, CAK-kinase p42
75 CDK20/CycT1 CDK20, CAK-kinase p42, CCRK, CDCH, p42, PNQALRE
76 CDK3/CycC CDK3, CDKN3
77 CDK3/CycE1 CDK3, n/a
78 CDK4/CycD1 CDK4, CMM3, PSK-J3, MGC14458
79 CDK4/CycD2 CDK4, CMM3, PSK-J3
80 CDK4/CycD3 CDK4, CMM3, PSK-J3, MGC14458
81 CDK5/p25NCK CDK5, PSSALRE
82 CDK5/p35NCK CDK5, PSSALRE
83 CDK6/CycD1 CDK6, PLSTIRE, MGC59692
84 CDK6/CycD2 CDK6, PLSTIRE
85 CDK6/CycD3 CDK6, PLSTIRE
86 CDK7/CycH/MAT1 CDK7, CAK1, CDKN7, STK1, p39MO15
87 CDK8/CycC CDK8, K35
88 CDK9/CycK CDK9, C-2k, CDC2L4, PITALRE, TAK, CDC2-related kinase
89 CDK9/CycT1 CDK9, C-2k, CDC2L4K35, PITALRE, TAK
90 CHK1 CHEK1, n/a
91 CHK2 CHEK2, CDS1, HuCds1, PP1425, RAD53, bA444G7
92 CK1alpha1 CSNK1A1, CK1, HLCDGP1, PRO2975, CK1-alpha1
93 CK1delta CSNK1D, HCKID, CK1-delta
94 CK1epsilon CSNK1E, CKIe, HCKIE, MGC10398, CK1-epsilon
95 CK1gamma1 CSNK1G1, CK1-gamma1
96 CK1gamma2 CSNK1G2, CK1g2, CK1-gamma2
97 CK1gamma3 CSNK1G3, CK1-gamma3
98 CK2alpha1 CSNK2A1, CKII, CK2A1, CK2-alpha1
99 CK2alpha2 CSNK2A2, CK2-alpha2
100 CLK1 CLK1, CLK, CLK/STY
101 CLK2 CLK2, MGC61500, clk2, hCLK2
102 CLK3 CLK3, PHCLK3, PHCLK3/152
103 CLK4 CLK4, DKFZp686A20267, CDC-like kinase 4
104 COT MAP3K8, EST, ESTF, TPL2, Tpl-2, c-COT
105 CSF1R CSF1R, C-FMS, CD115, CSF-1-R, CSFR, FIM2, FMS, CSF1-R
106 CSK CSK, n/a
107 DAPK1 DAPK1, n/a
108 DAPK2 DAPK2, DRP-1
109 DAPK3 DAPK3, ZIP, ZIPK
110 DCAMKL2 DCLK2, DCLK, KIAA0369
111 DDR2 DDR2, MIG20a, NTRKR3, TKT, TYRO10, DDR2 wt
112 DDR2 N456S DDR2, MIG20a, NTRKR3, TKT, TYRO10
113 DDR2 T654M DDR2, MIG20a, NTRKR3, TKT, TYRO10
114 DMPK DMPK, DM, DM1, DM1PK, DMK
115 DNAPK PRKDC, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350, DNA-PK
116 DYRK1A DYRK1A, DYRK, DYRK1, HP86, MNB, MNBH
117 DYRK1B DYRK1B, MIRK
118 DYRK2 DYRK2
119 DYRK3 DYRK3, DYRK5, RED, REDK
120 DYRK4 DYRK4
121 EEF2K EEF2K, HSU93850, MGC45041, eEF-2K
122 EGFR EGFR, ERBB, mENA, ERBB1, EGF-R wt
123 EGFR C797S EGF-R, ERBB, ERBB1, EGF-R C797S
124 EGFR C797S/L858R EGFR, ERBB, ERBB1, mENA, EGF-R C797S/L858R
125 EGFR d746-750 EGFR, ERBB, mENA, ERBB1, EGF-R d746-750
126 EGFR d746-750/T790M/C797S EGFR, ERBB, ERBB1, mENA, EGF-R d746-750/T790M/C797S
127 EGFR d746-750/T790M/C797S/L858R EGFR, ERBB, mENA, ERBB1, EGF-R d746-750/T790M/C797S/L858R
128 EGFR d747-749/A750P EGFR, ERBB, mENA, ERBB1, EGF-R d747-749/A750P
129 EGFR d747-752/P753S EGFR, ERBB, mENA, ERBB1, EGF-R d747-752/P753S
130 EGFR d752-759 EGFR, ERBB, mENA, ERBB1, EGF-R d752-759
131 EGFR G719C EGFR, ERBB, mENA, ERBB1, EGF-R G719C
132 EGFR G719S EGFR, ERBB, mENA, ERBB1, EGF-R G719S
133 EGFR L718Q EGFR, ERBB, ERBB1, mENA
134 EGFR L858R EGFR, ERBB, ERBB1, EGF-R L858R
135 EGFR L861Q EGFR, ERBB, mENA, ERBB1, EGF-R L861Q
136 EGFR T790M EGFR, ERBB, ERBB1, EGF-R T790M
137 EGFR T790M/C797S/L858R EGFR, ERBB, ERBB1, EGF-R T790M/C797S/L858R
138 EGFR T790M/L858R EGFR, ERBB, ERBB1, EGF-R T790M/L858R
139 EIF2AK2 EIF2AK2, EIF2AK1, PKR, PRKR
140 EIF2AK3 EIF2AK3, DKFZp781H1925, PEK, PERK, WRS
141 EML4 ALK ALK
142 EML4 ALK F1174L ALK
143 EPHA1 EPHA1, EPH, EPHT, EPHT1
144 EPHA2 EPHA2, ECK
145 EPHA3 EPHA3, ETK, ETK1, EphA3, HEKECK, HEK4, TYRO4
146 EPHA4 EPHA4, HEK8, SEK, TYRO1
147 EPHA5 EPHA5, CEK7, EHK1, EphA5, HEK7, Hek7, TYRO4
148 EPHA6 EPHA6, EHK2, EHK-2, EPA6
149 EPHA7 EPHA7, EHK3, HEK11
150 EPHA8 EPHA8, EEK, EphA8, HEK3, KIAA1459
151 EPHB1 EPHB1, ELK, NET, Hek6, EPHT2
152 EPHB2 EPHB2, DRT, ERK, Hek5, EPHT3, Tyro5
153 EPHB3 EPHB3, ETK2, HEK2, TYRO6
154 EPHB4 EPHB4, HTK, MYK1, TYRO11
155 ERBB2 ERBB2, NEU, NGL, HER2, TKR1, HER-2, ERBB2 wt
156 ERBB2 775YVMA776 ERBB2, CD340, HER2, MLN19, NGL, TKR1
157 ERBB4 ERBB4, n/a
158 ERK1 MAPK3, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3
159 ERK2 MAPK1, ERK, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41
160 ERK5 MAPK7, BMK1, ERK4, PRKM7
161 ERK7 MAPK15, ERK8, MAPK15
162 FAK PTK2, FADK, pp125FAK, FAK aa2-1052
163 FAK aa411-686 PTK2, FADK, pp125FAK
164 FER FER, TYK3, c-FER, p94-FER
165 FES FES, FPS
166 FGFR1 FGFR1, H2, H3, H4, H5, CEK, FLG, FLT2, KAL2, BFGFR, C-FGR, N-SAM, FGF-R1 wt
167 FGFR1 V561M FGFR1, FGFR-1, bFGF-R, FLT2, CEK, CD331, FGF-R1 V561M
168 FGFR2 FGFR2, FGFR2, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, FGFR-2, JWS, KGFR, KSAM, K-SAM, TK14, TK25
169 FGFR3 FGFR3, ACH, CD333, CEK2, FGFR-3, HSFGFR3EX, JTK4, FGF-R3 wt
170 FGFR3 G697C FGFR3, ACH, CD333, CEK2, FGFR-3, HSFGFR3EX, JTK4, FGF-R3 G697C
171 FGFR3 K650E FGFR3, ACH, CD333, CEK2, FGFR-3, HSFGFR3EX, JTK4, FGF-R3 K650E
172 FGFR3 K650M FGFR3, ACH, CD333, CEK2, FGFR-3, HSFGFR3EX, JTK4, FGF-R3 K650M
173 FGFR4 FGFR4, TKF, JTK2, MGC20292, FGF-R4
174 FGR FGR, SRC2, c-fgr, p55c-fgr
175 FLT3 FLT3, CD135, FLK2, STK-1, STK1, FLT3 wt
176 FLT3 D835Y FLT3, CD135, FLK2, STK-1, STK1
177 FLT3 ITD FLT3, CD135, FLK2, STK-1, STK1
178 FRK FRK, GTK, PTK5, RAK
179 FYN FYN, SLK, SYN, p59-Fyn, FYN wt
180 FYN Y531F FYN, SLK, SYN, p59-FYN, cFYN
181 GRK2 ADRBK1
182 GRK3 ADRBK2
183 GRK4 GRK4, GPRK2L, GPRK4, GRK4a, IT11
184 GRK5 GRK5
185 GRK6 GRK6
186 GRK7 GRK7
187 GSG2 GSG2, Haspin
188 GSK3alpha GSK3A, GSK3-alpha
189 GSK3beta GSK3B, GSK3-beta
190 HCK HCK, JTK9
191 HIPK1 HIPK1, KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2
192 HIPK2 HIPK2, PRO0593
193 HIPK3 HIPK3, ANPK, DYRK6, FIST, FIST3, PKY, YAK1
194 HIPK4 HIPK4, FLJ32818
195 HRI EIF2AK1, HCR
196 IGF1R IGF1R, JTK13, IGF1-R
197 IKKalpha CHUK, IKBKA, IKK1, IKKA, NFKBIKA, TCF16, IKK-alpha
198 IKKbeta IKBKB, IKK2, IKKB, NFKBIKB, IKK-beta
199 IKKepsilon IKBKE, IKKE, IKKI, IKK-i, KIAA0151, IKK-epsilon
200 INSR INSR, INS-R
201 INSRR INSRR, IRR, INSR-R
202 IRAK1 IRAK1, IRAK, Pelle
203 IRAK4 IRAK4, REN64, NY-REN-64, IRAK4 (untagged)
204 ITK ITK, EMT 2, LYK 2, PSCTK2 2, IL2-inducible T-cell kinase
205 JAK1 JAK1, JAK1A, JAK1B, JTK3, JAK1 aa583-1154 wt
206 JAK1 aa850-1154 JAK1, JAK-1, JAK1A, AK1B, JAK1 aa850-1154 wt
207 JAK1 S729C JAK1, JAK1A, JAK1B, JTK3, JAK1 aa583-1154 S729C
208 JAK2 JAK2, n/a
209 JAK3 JAK3, JAKL, L-JAK, LJAK
210 JNK1 MAPK8, PRKM8, SAPK1, JNK1-alpha1
211 JNK2 MAPK9, PRKM9, p54aSAPK, JNK2-alpha2
212 JNK3 MAPK10, JNK3A, p54bSAPK
213 KIT KIT, C-Kit, PBT, CD117, SCFR, c-kit, KIT wt
214 KIT A829P KIT, C-Kit, PBT, CD117, SCFR, c-kit
215 KIT D816H KIT, C-Kit, PBT, CD117, SCFR, c-kit
216 KIT D816V KIT, C-Kit, PBT, CD117, SCFR, c-kit
217 KIT T670I KIT, CD117, SCFR, PBT, C-Kit
218 KIT V559D KIT, C-Kit, PBT, CD117, SCFR, c-kit
219 KIT V559D/T670I KIT, C-Kit, PBT, CD117, SCFR, c-kit
220 KIT V559D/V654A KIT, C-Kit, PBT, CD117, SCFR, c-kit
221 KIT V560G KIT, C-Kit, PBT, CD117, SCFR, c-kit
222 KIT V654A KIT, C-Kit, PBT, CD117, SCFR, c-kit
223 LCK LCK, n/a
224 LIMK1 LIMK1, LIMK
225 LIMK2 LIMK2
226 LRRK2 LRRK2, PARK8, ROCO2, FLJ45829, DKFZp434H2111, LRRK2 wt
227 LRRK2 G2019S LRRK2, PARK8, ROCO2, FLJ45829, DKFZp434H2111
228 LRRK2 I2020T LRRK2, PARK8, ROCO2, FLJ45829, DKFZp434H2111
229 LRRK2 R1441C LRRK2, PARK8, ROCO2, FLJ45829, DKFZp434H2111
230 LTK LTK, TYK1
231 LYN LYN, JTK8
232 MAP3K1 MAP3K1, MAPKKK1, MEKK, MEKK1
233 MAP3K10 MAP3K10, MLK2, MST, MEKK10
234 MAP3K11 MAP3K11, MGC17114, MLK-3, PTK1, SPRK
235 MAP3K7/MAP3K7IP1 MAP3K7, TAK1, TGF1a, MEKK7
236 MAP3K9 MAP3K9, MLK1, PRKE1, MEKK9
237 MAP4K2 MAP4K2, BL44, GCK, RAB8IP
238 MAP4K4 MAP4K4, HGK, MEKKK4, NIK
239 MAP4K5 MAP4K5, KHS1, GCKR, KHS, MAPKKKK5
240 MAPKAPK2 MAPKAPK2, n/a
241 MAPKAPK3 MAPKAPK3, 3PK, MAPKAP, MAPKAP3
242 MAPKAPK5 MAPKAPK5, PRAK
243 MARK1 MARK1, KIAA1477
244 MARK2 MARK2, EMK1, MGC99619, PAR-1, ELKL motif kinase 1
245 MARK3 MARK3, CTAK1, KP78, PAR1A
246 MARK4 MARK4, KIAA1860, MARKL1
247 MASTL MASTL, GLW, GREATWALL, GWL, hGWL, MAST-L, THC2
248 MATK MATK, CHK, CTK, DKFZp434N1212, HHYLTK, HYL, Lsk, MGC1708, MGC2101
249 MEK1 MAP2K1, MAPKK1, MKK1, PRKMK1, MEK1 wt
250 MEK1 F53L MAP2K1, MAP2K1, MAPKK1, MAPKK 1, MKK1, PRKMK1
251 MEK1 SESE MAP2K1, MAPKK1, MKK1, PRKMK1, MEK1 S218E/S222E
252 MEK2 MAP2K2, MAPKK2, MKK2, PRKMK2
253 MEK5 MAP2K5, MAP2K5, MAPKK5, MKK5, PRKMK5
254 MEKK2 MAP3K2, MAPKKK2, MEKK2B
255 MEKK3 MAP3K3, MAPKKK3, MEK kinase3
256 MELK MELK, PK38
257 MERTK MERTK, MER, MER-PEN, RP38
258 MET MET, HGFR, RCCP2, MET wt
259 MET D1228H MET, HGFR, RCCP2
260 MET D1228N MET, HGFR, RCCP2
261 MET F1200I MET, HGFR, RCCP2
262 MET G1163R MET, HGFR, RCCP2
263 MET L1195V MET, HGFR, RCCP2
264 MET M1250T MET, HGFR, RCCP2
265 MET Y1230A MET, HGFR, RCCP2
266 MET Y1230C MET, HGFR, RCCP2
267 MET Y1230D MET, HGFR, RCCP2
268 MET Y1230H MET, HGFR, RCCP2
269 MET Y1235D MET, HGFR, RCCP2
270 MINK1 MINK1, B55, YSK2, MAP4K6, ZC3
271 MKK4 MAP2K4, JNKK, JNKK1, MAPKK4, MEK4, PRKMK4, SEK, SERK1
272 MKK6 SDTD MAP2K6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3, MKK6 S207D/T211D
273 MKK7 MAP2K7, MAPKK7, MEK7, PRKMK7
274 MKNK1 MKNK1, MNK1
275 MKNK2 MKNK2, MNK2, GPRK7
276 MLK4 n/a, KIAA1804
277 MST1 STK4, KRS2, YSK3
278 MST2 STK3, MST-2, KRS1
279 MST3 STK24, MST-3, MST3B, STK3
280 MST4 MST4, MASK
281 MTOR FRAP1, FRAP, FRAP2, RAFT1, RAPT1, rapamycin target protein
282 MUSK MUSK, n/a
283 MYLK MYLK, smMLCK, FLJ12216, KRP, MLCK, MLCK108, MLCK210
284 MYLK2 MYLK2, KMLC, MLCK, skMLCK
285 MYLK3 MYLK3, caMLCK, MLCK2, MYLK2
286 NEK1 NEK1, NY-REN-55
287 NEK11 NEK11, FLJ23495
288 NEK2 NEK2, NLK1, HsPK21, HsPK 21
289 NEK3 NEK3, HSPK36, MGC29949
290 NEK4 NEK4, NRK2, STK2
291 NEK6 NEK6, SID6-1512
292 NEK7 NEK7, n/a
293 NEK9 NEK9, DKFZp434D0935, MGC16714, NERCC, NERCC1, Nek8
294 NIK MAP3K14, FTDCR1B, HS, HSNIK
295 NLK NLK, n/a
296 NPM1 ALK n/a, n/a
297 NPM1 ALK F1174L n/a, n/a
298 p38alpha MAPK14, p38-alpha
299 p38beta MAPK11, p38-beta
300 p38delta MAPK13, p38-delta
301 p38gamma MAPK12, ERK-6, ERK3, ERK5, ERK6, PRKM12, SAPK-3, SAPK3, p38-gamma
302 PAK1 PAK1, PAKalpha
303 PAK2 PAK2, PAK65, PAKgamma
304 PAK3 PAK3, CDKN1A, MRX30, OPHN3, PAK3beta, bPAK, hPAK3
305 PAK4 PAK4, n/a
306 PAK6 PAK6, PAK5
307 PAK7 PAK7, KIAA1264, MGC26232
308 PASK PASK, DKFZP434O051, DKFZp686P2031, KIAA0135, PASKIN, STK3
309 PBK PBK, TOPK, SPK, Nori-3, FLJ14385
310 PDGFRalpha PDGFRA, PDGFR2, CD140a, PDGFR-alpha wt
311 PDGFRalpha D842V PDGFRA, PDGFR2, CD140a, PDGFR-alpha D842V
312 PDGFRalpha T674I PDGFRA, PDGFR2, CD140a, PDGFR-alpha T674I
313 PDGFRalpha V561D PDGFRA, PDGFR2, CD140a, PDGFR-alpha V561D
314 PDGFRbeta PDGFRB, JTK12, PDGFR, CD140B, PDGFR1, PDGF-R-beta, PDGFR-beta
315 PDK1 PDPK1, PKB-like
316 PHKG1 PHKG1, PHKg1
317 PHKG2 PHKG2, PHKg2
318 PI4K2A PI4K2A, PI4KII, PIK42A, RP11-548K23.6
319 PI4K2B PI4K2B, PI4KIIB, PI4KII-BETA, PIK42B
320 PI4KB PI4KB, NPIK, pi4K92, PI4K92, PI4Kbeta, PI4KBETA, PI4K-beta, PI4K-BETA, PI4KIIIBETA, PIK4CB
321 PIK3C2A PIK3C2A, CPK, MGC142218, PI3-K-C2A
322 PIK3C2B PIK3C2B, C2-PI3K, PI3K-C2beta
323 PIK3C2G PIK3C2G, PI3K-C2GAMMA, PI3K-C2-gamma
324 PIK3C3 PIK3C3, hVps34, MGC61518, PI3-kinase type 3, PI3K type 3, Vps34, VPS34
325 PIK3CA/PIK3R1 PIK3CA, MGC142161, MGC142163, p110-alpha, PI3K, PI3K-alpha
326 PIK3CB D1067A/PIK3R1 P110BETA, PI3K, PI3KBETA, PI3K-beta, PIK3C1
327 PIK3CB D1067V/PIK3R1 PIK3CB, P110BETA, PI3K, PI3KBETA, PI3K-beta, PIK3C1
328 PIK3CB D1067Y/PIK3R1 P110BETA, PI3K, PI3KBETA, PI3K-beta, PIK3C1
329 PIK3CB E1051K/PIK3R1 PIK3CB, P110BETA, PI3K, PI3KBETA, PI3K-beta, PIK3C1
330 PIK3CB E633K/PIK3R1 PIK3CB, P110BETA, PI3K, PI3KBETA, PI3K-beta, PIK3C1
331 PIK3CB L1049R/PIK3R1 PIK3CB
332 PIK3CB/PIK3R1 PIK3CB, PI3K, PI3KBETA, PI3K-beta, PIK3C1, p110-beta, PIK3CB wt/PIK3R1
333 PIK3CD/PIK3R1 PIK3CD, p110D, P110DELTA, PI3K, PI3K-delta, p110-delta
334 PIK3CG PIK3CG, p120-PI3K, PI3CG, PI3K, PI3Kgamma, PI3K-gamma, p110-gamma
335 PIM1 PIM1, PIM
336 PIM2 PIM2, n/a
337 PIM3 PIM3, n/a
338 PIP5K1A PIP5K1A, PIP5K1-alpha, PIP5KIalpha, PtdIns(4)P-5-kinase 1 alpha
339 PIP5K1B PIP5K1B, MSS4, PIP5K1-beta, STM7
340 PIP5K1C PIP5K1C, PIP5K1-gamma, PIP5Kgamma, PIP5K-GAMMA, PIPKIg_v4
341 PKA PRKACA, MGC48865, PKA
342 PKCalpha PRKCA, PKCA, PRKACA, PKC-alpha
343 PKCbeta1 PRKCB1, PKCB, PRKCB, PRKCB2, MGC41878, PKC-beta, PKC-beta1
344 PKCbeta2 PRKCB1, PKCB, PRKCB, PRKCB2, MGC41878, PKC-beta, PKC-beta2
345 PKCdelta PRKCD, MAY1, MGC49908, nPKC-delta, PKC-delta
346 PKCepsilon PRKCE, PKCE, nPKC-epsilon, PKC-epsilon
347 PKCeta PRKCH, PKC-L, PKCL, PRKCL, nPKC-eta, PKC-eta
348 PKCgamma PRKCG, PKCC, PKCG, SCA14, MGC57564, PKC-gamma
349 PKCiota PRKCI, PKCI, DXS1179E, MGC26534, nPKC-iota, PKC-iota
350 PKCmu PRKD1, PKD, PKCM, PKC-MU, PKC-mu
351 PKCnu PRKD3, EPK2, PKC-nu
352 PKCtheta PRKCQ, PRKCT, nPKC-theta, PKC-theta
353 PKCzeta PRKCZ, PKC2, PKC-zeta
354 PKMYT1 PKMYT1, MYT1
355 PKMzeta PRKCZ, PKM-zeta, nPKC-zeta, PKC2, PKC-zeta wt aa184-592 (PKM-zeta)
356 PKN3 PKN3, PKNbeta, RP11-545E17.1
357 PLK1 PLK1, PLK, STPK13
358 PLK3 PLK3, CNK, FNK, PRK
359 PRK1 PKN1, DBK, PKN, PAK1, PRK1, PRKCL1, MGC46204
360 PRK2 PKN2, PRKCL2, PAK-2
361 PRKD2 PRKD2, PKD2, HSPC187
362 PRKG1 PRKG1, PKG1, CGKI, MGC71944, PGK, PRKG1B, PRKGR1B, cGKIBETA, cGKI-alph
363 PRKG2 PRKG2, PKG2, PRKGR2, cGKII
364 PRKX PRKX, PKX1
365 PYK2 PTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK, CAK beta
366 RAF1 YDYD RAF1, c-RAF, RAF1 Y340D/Y341D (untagged)
367 RET RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1, RET wt
368 RET E762Q RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
369 RET G691S RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
370 RET G810C RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
371 RET G810R RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
372 RET G810S RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
373 RET M918T RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
374 RET R749T RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
375 RET R813Q RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
376 RET S891A RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
377 RET V804E RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
378 RET V804L RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
379 RET V804M RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
380 RET Y791F RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
381 RET Y806H RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
382 RIPK2 RIPK2, CARD3, CARDIAK, CCK, GIG30, RICK, RIP-2, RIP2
383 RIPK4 RIPK4, ANKK2, ANKRD3, DIK, MGC129992, MGC129993, PKK, RIP4
384 RIPK5 DSTYK, SgK496, SHIK
385 ROCK1 ROCK1, P160ROCK
386 ROCK2 ROCK2, KIAA0619, ROC2
387 RON MST1R, CD136, CDw136, PTK8
388 ROS ROS1, MCF3
389 RPS6KA1 RPS6KA1, RSK3, HU-1, MAPKAPK1A, RSK, RSK1
390 RPS6KA2 RPS6KA2, RSK1, HU-2, MAPKAPK1C, RSK, RSK3
391 RPS6KA3 RPS6KA3, HU-2, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2
392 RPS6KA4 RPS6KA4, MSK2, RSK-B
393 RPS6KA5 RPS6KA5, MSK1, EC 2.7.11, MGC1911, MSPK1, RLPK, RSKL
394 RPS6KA6 RPS6KA6, RSK4
395 S6K RPS6KB1, S6K1, STK14A
396 S6Kbeta RPS6KB2, KLS, P70-beta-1, P70-beta-2, S6K-beta2, S6K2, SRK, p70S6Kb, S6K-beta
397 SAK PLK4, SAK, STK18
398 SGK1 SGK, n/a
399 SGK2 SGK2, H-SGK2, dJ138B7.2
400 SGK3 SGKL, CISK, SGK2, SGK3
401 SIK1 SIK1, MSK, SNF1LK, SIK, SIK-1, SNF1LK
402 SIK2 SIK2, QIK, SNF1LK2
403 SIK3 SIK3, L19, QSK, SIK-3
404 SLK SLK, KIAA0204, STK2, bA16H23.1, se20-9
405 SNARK NUAK2, DKFZp434J037
406 SNK PLK2, SNK
407 SRC SRC, ASV, SRC1, c-SRC, p60-Src, SRC (GST-HIS-tag)
408 SRMS SRMS, C20orf148, SRM, dJ697K14.1
409 SRPK1 SRPK1, SFRSK1
410 SRPK2 SRPK2, SFRSK2
411 STK17A STK17A, DRAK1
412 STK23 SRPK3, MSSK1, MGC102944
413 STK25 STK25, DKFZp686J1430, SOK1, YSK1
414 STK33 STK33
415 STK39 STK39, STLK3, DCHT, SPAK
416 SYK SYK, n/a, SYK aa1-635
417 SYK aa356-635 SYK
418 TAOK2 TAOK2, KIAA0881, MAP3K17, PSK, PSK1, TAO1, TAO2
419 TAOK3 TAOK3, DPK, JIK, MAP3K18, TAO kinase 3
420 TBK1 TBK1, CDC37, HSPCA, HSPCB, IKBKG, NAK, T2K, TANK, TRAF2
421 TEC TEC, PSCTK4
422 TGFBR1 TGFBR1, ALK5, ACVRLK4, TGFB-R1
423 TGFBR2 TGFBR2, HNPCC6, MFS2, RIIC, TGFR-2, TGFbeta-RII, TGFB-R2
424 TIE2 TEK, VMCM, TIE-2, VMCM1, CD202B, TIE2 wt
425 TIE2 R849W TEK, VMCM, TIE-2, VMCM1, CD202B
426 TIE2 Y1108F TEK, VMCM, TIE-2, VMCM1, CD202B
427 TIE2 Y897S TEK, VMCM, TIE-2, VMCM1, CD202B
428 TLK1 TLK1, PKU-beta, KIAA0137
429 TLK2 TLK2, MGC44450, PKU-ALPHA
430 TNK1 TNK1, n/a
431 TRKA NTRK1, MTC, TRK, TRK1, TRKA, TRK-A wt
432 TRKA G667C MTC, TRK1, TRKA, TRK-A G667C
433 TRKB NTRK2, GP145-TrkB, TRKB, Trk-B, TRK-B
434 TRKC NTRK3, GP145-TrkC, TRKC, Trk-C, TRK-C
435 TSF1 STK16, KRCT, MPSK, PKL12
436 TSK2 TSSK2, DGS-G, SPOGA2, FLJ38613
437 TSSK1 TSSK1, FKSG81, SPOGA4, STK22D
438 TTBK1 TTBK1, BDTK, TTBK1 aa1-1321
439 TTBK1 aa1-480 TTBK1, BDTK
440 TTBK2 TTBK2, BDTK, KIAA1855, RP3-330M21.4
441 TTK TTK, ESK, MPS1L1, PYT
442 TXK TXK, BTKL, PSCTK5, PTK4, RLK
443 TYK2 TYK2, JTK1
444 TYRO3 TYRO3, BYK, Brt, Dtk, Sky, Tif
445 ULK2 ULK2, ATG1B, KIAA0623, Unc51.2
446 VEGFR1 FLT1, FLT, VEGF-R1
447 VEGFR2 KDR, FLK1, VEGFR, VEGF-R2
448 VEGFR3 FLT4, PCL, VEGF-R3
449 VRK1 VRK1, n/a
450 VRK2 VRK2, n/a
451 WEE1 WEE1, WEE1hu
452 WNK1 WNK1, KDP, KIAA0344, PHA2C, PRKWNK1
453 WNK2 WNK2, KIAA1760, NY-CO-43, P/OKcl.13, PRKWNK2, SDCCAG43
454 WNK3 WNK3, KIAA1566, PRKWNK3
455 YES YES, C-YES, HsT441, P61-YES
456 ZAK MLTK, mlklak, AZK
457 ZAP70 ZAP70, SRK, STD, TZK, ZAP-70
EXCEL

Info in Brief

Kinase Panel

449 kinases, including 91 disease-relevant kinase
mutants and 20 lipid kinases

Assay Technologies

Protein kinases: FlashPlate™-based radiometric assay;
lipid kinases: ADP-Glo™ assay technology (Promega)

ATP conc

App. ATP-Km for each kinase

Testing Modes

Single concentration measurement or IC50 profiling
(10 conc in semi-log steps)

Cpd Submission

100 x Stock solution in 100% DMSO or
pre-weighed powder (request guidelines)

Report

Detailed report for each project
Sample report will be provided upon request

Turnaround Time

No fixed time slots; first come - first served;
routinely within 10 working days

Info Sheets

Method: Radiometric Assay, Method: ATP-Glo™ Assay

Guidelines for Cpd Submission

Guidelines       SPF       CSF