Biochemical Assay Services

Free Choice Kinase Assay Projects / Kinase Assays

Field of Application

Free choice kinase assay projects allow characterization of your test compounds in a total flexible mode. For each project you can freely define (i) the number of kinase assays, (ii) the number of test compounds (iii) and the number of data points for each test compound (i.e. number of concentrations and replicates). All kinase assays are designed to measure biochemical kinase activity.

Our Services

Number Kinase Synonyms
1 ABL1 ABL1, ABL, JTK7, p150, c-ABL, v-abl, ABL1 wt
2 ABL1 E255K ABL1, c-Abl, JTK7, p150
3 ABL1 F317I ABL1, ABL, JTK7, p150, c-ABL, v-abl
4 ABL1 G250E ABL1, ABL, JTK7, p150, c-ABL, v-abl
5 ABL1 H396P ABL1, ABL, JTK7, p150, c-ABL, v-abl
6 ABL1 M351T ABL1, ABL, JTK7, p150, c-ABL, v-abl
7 ABL1 Q252H ABL1, ABL, JTK7, p150, c-ABL, v-abl
8 ABL1 T315I ABL1, ABL, JTK7, p150, c-ABL, v-abl
9 ABL1 Y253F ABL1, ABL, JTK7, p150, c-ABL, v-abl
10 ABL2 ABL2, ABLL, ARG
11 ACK1 TNK2, ACK, p21cdc42Hs, Activated CDC42 kinase 1
12 ACVR1 ACVR1, ACTRI, ACVRLK2, ALK2, SKR1, ACV-R1
13 ACVR1B ACVR1B, ACTRIB, ACVRLK4, ALK4, SKR2, ACV-R1B
14 ACVR2A ACVR2, ACTRII, ACV-R2A
15 ACVR2B ActR-IIB, ACTRIIB, ACV-R2B
16 ACVRL1 ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, ACV-RL1
17 AKT1 AKT1, PKB, RAC, PRKBA, RAC-ALPHA, AKT1 aa1-480
18 AKT1 aa106-480 AKT1, PKB, RAC, PRKBA, RAC-ALPHA
19 AKT2 AKT2, PKBB, PKBBETA, PKB beta, PRKBB, RAC-beta, RAC-PK-beta, AKT2 aa1-481
20 AKT2 aa107-481 AKT2, PKBB, PKBBETA, PKB beta, PRKBB, RAC-beta, RAC-PK-beta
21 AKT3 AKT3, PKBG, PKB gamma, PRKBG, RAC-gamma, RAC-PK-gamma, STK-2, DKFZp434N0250, AKT3 aa1-479
22 AKT3 aa106-479 AKT3, PKBG, PRKBG, STK-2, RAC-gamma, RAC-PK-gamma
23 ALK ALK, CD246, NBLST3, ALK wt (GST-HIS-tag)
24 ALK C1156Y ALK, CD246, NBLST3, ALK C1156Y (GST-HIS-tag)
25 ALK F1174L ALK, CD246, NBLST3, ALK F1174L (GST-HIS-tag)
26 ALK F1174S ALK, CD246, NBLST3, ALK F1174S (GST-HIS-tag)
27 ALK G1202R ALK, CD246, NBLST3, ALK G1202R (GST-HIS-tag)
28 ALK L1196M ALK, CD246, NBLST3, ALK L1196M (GST-HIS-tag)
29 ALK R1275Q ALK, CD246, NBLST3, ALK R1275Q (GST-HIS-tag)
30 AMPKalpha1 PRKAA1, MGC33776, MGC57364, AMPK-alpha1 aa1-550
31 AMPKalpha1 aa1-312 PRKAA1, MGC33776, MGC57364, AMPK-alpha1 aa1-312
32 ARAF YDYD ARAF, ARAF1
33 ARK5 NUAK1, KIAA0537
34 ASK1 MAP3K5, ASK1, MAPKKK5, MEKK5
35 AuroraA AURKA, AIK, ARK1, AURA, BTAK, STK15, MGC34538, STK6, Aurora-A
36 AuroraB AURKB, AIK2, AIM1, ARK2, AurB, IPL1, STK5, AIM-1, STK12, Aurora-B
37 AuroraC AURKC, AIE2, AIK3, STK13, Aurora-C
38 AXL AXL, EC, UFO
39 BLK BLK, n/a
40 BMPR1A BMPR1A, SKR5, CD292, ALK3, ACVRLK3
41 BMPR1B BMPR1B, ALK6, CDw293
42 BMX BMX, ETK, PSCTK2, PSCTK3
43 BRAF BRAF, B-Raf, B-raf-1, BRAF1, RAFB1, B-RAF wt
44 BRAF V600E BRAF, B-Raf, B-raf-1, BRAF1, RAFB1, B-RAF V600E
45 BRK PTK6, n/a
46 BRSK1 BRSK1, KIAA1811
47 BRSK2 C11orf7, FLJ41362, HUSSY-12, PEN11B, SAD1, STK29
48 BTK BTK, AGMX1, AT, ATK, BPK, PSCTK1
49 BUB1B BUB1B, BUBR1, Bub1A, MAD3L, hBUBR1
50 CAMK1D CAMK1D, CKLiK, CaM-K1, CaMKID
51 CAMK2A CAMK2A, CAMKA, KIAA0968
52 CAMK2B CAMK2B, CAM2, CAMK2, CAMKB, MGC29528
53 CAMK2D CAMK2D, CAMKD, MGC44911, CaMKII delta
54 CAMK2G CAMK2G, CAMK, CAMK-II, CAMKG, MGC26678
55 CAMK4 CAMK4, CaMK-GR, MGC36771
56 CAMKK1 CAMKK1, CAMKKA, DKFZp761M0423, MGC34095
57 CAMKK2 CAMKK2, CAMKK, CAMKKB, KIAA0787, MGC15254
58 CCDC6 RET CCDC6-RET, CCDC6-RETa, CCDC6-RET
59 CDC42BPA CDC42BPA, MRCK-alpha
60 CDC42BPB CDC42BPB, MRCK-beta, MRCKb
61 CDC7/DBF4 CDC7, CDC7L1, HsCdc7, HsCDC7, Hsk1, huCdc7
62 CDK1/CycA2 CDC2, p34
63 CDK1/CycB1 CDC2, p34
64 CDK1/CycE1 CDC2, p34
65 CDK12 R722C/CycK CDK12, CRKRS, CRK7
66 CDK12/CycK CDK12, CRKRS, CRK7, CDK12 wt/CycK
67 CDK13/CycK CDK13, CDC2L, CDC2L5, CHED
68 CDK16/CycY CDK16, PCTAIRE1, PCTAIRE, PCTGAIRE, PCTK1
69 CDK17/p35NCK CDK17, PCTAIRE2, PCTK2
70 CDK18/CycY CDK18, PCTAIRE, PCTAIRE3, PCTK3
71 CDK19/CycC CDK19, CDC2L6, CDK11
72 CDK2/CycA2 CDK2, p33(CDK2)
73 CDK2/CycD1 CDK2, p33
74 CDK2/CycE1 CDK2, p33(CDK2)
75 CDK20/CycH CDK20, CAK-kinase p42
76 CDK20/CycT1 CDK20, CAK-kinase p42, CCRK, CDCH, p42, PNQALRE
77 CDK3/CycC CDK3, CDKN3
78 CDK3/CycE1 CDK3, n/a
79 CDK4/CycD1 CDK4, CMM3, PSK-J3, MGC14458
80 CDK4/CycD2 CDK4, CMM3, PSK-J3
81 CDK4/CycD3 CDK4, CMM3, PSK-J3, MGC14458
82 CDK5/p25NCK CDK5, PSSALRE
83 CDK5/p35NCK CDK5, PSSALRE
84 CDK6/CycD1 CDK6, PLSTIRE, MGC59692
85 CDK6/CycD2 CDK6, PLSTIRE
86 CDK6/CycD3 CDK6, PLSTIRE
87 CDK7/CycH/MAT1 CDK7, CAK1, CDKN7, STK1, p39MO15
88 CDK8/CycC CDK8, K35
89 CDK9/CycK CDK9, C-2k, CDC2L4, PITALRE, TAK, CDC2-related kinase
90 CDK9/CycT1 CDK9, C-2k, CDC2L4K35, PITALRE, TAK
91 CHK1 CHEK1, n/a
92 CHK2 CHEK2, CDS1, HuCds1, PP1425, RAD53, bA444G7
93 CK1alpha1 CSNK1A1, CK1, HLCDGP1, PRO2975, CK1-alpha1
94 CK1delta CSNK1D, HCKID, CK1-delta
95 CK1epsilon CSNK1E, CKIe, HCKIE, MGC10398, CK1-epsilon
96 CK1gamma1 CSNK1G1, CK1-gamma1
97 CK1gamma2 CSNK1G2, CK1g2, CK1-gamma2
98 CK1gamma3 CSNK1G3, CK1-gamma3
99 CK2alpha1 CSNK2A1, CKII, CK2A1, CK2-alpha1
100 CK2alpha2 CSNK2A2, CK2-alpha2
101 CLK1 CLK1, CLK, CLK/STY
102 CLK2 CLK2, MGC61500, clk2, hCLK2
103 CLK3 CLK3, PHCLK3, PHCLK3/152
104 CLK4 CLK4, DKFZp686A20267, CDC-like kinase 4
105 COT MAP3K8, EST, ESTF, TPL2, Tpl-2, c-COT
106 CSF1R CSF1R, C-FMS, CD115, CSF-1-R, CSFR, FIM2, FMS, CSF1-R
107 CSK CSK, n/a
108 DAPK1 DAPK1, n/a
109 DAPK2 DAPK2, DRP-1
110 DAPK3 DAPK3, ZIP, ZIPK
111 DCAMKL2 DCLK2, DCLK, KIAA0369
112 DDR2 DDR2, MIG20a, NTRKR3, TKT, TYRO10, DDR2 wt
113 DDR2 N456S DDR2, MIG20a, NTRKR3, TKT, TYRO10
114 DDR2 T654M DDR2, MIG20a, NTRKR3, TKT, TYRO10
115 DMPK DMPK, DM, DM1, DM1PK, DMK
116 DNAPK PRKDC, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350, DNA-PK
117 DYRK1A DYRK1A, DYRK, DYRK1, HP86, MNB, MNBH
118 DYRK1B DYRK1B, MIRK
119 DYRK2 DYRK2
120 DYRK3 DYRK3, DYRK5, RED, REDK
121 DYRK4 DYRK4
122 EEF2K EEF2K, HSU93850, MGC45041, eEF-2K
123 EGFR EGFR, ERBB, mENA, ERBB1, EGF-R wt
124 EGFR C797S EGF-R, ERBB, ERBB1, EGF-R C797S
125 EGFR C797S/L858R EGFR, ERBB, ERBB1, mENA, EGF-R C797S/L858R
126 EGFR d746-750 EGFR, ERBB, mENA, ERBB1, EGF-R d746-750
127 EGFR d746-750/C797S EGFR, ERBB, ERBB1, EGF-R, mENA
128 EGFR d746-750/T790M/C797S EGFR, ERBB, ERBB1, mENA, EGF-R d746-750/T790M/C797S
129 EGFR d746-750/T790M/C797S/L858R EGFR, ERBB, mENA, ERBB1, EGF-R d746-750/T790M/C797S/L858R
130 EGFR d747-749/A750P EGFR, ERBB, mENA, ERBB1, EGF-R d747-749/A750P
131 EGFR d747-752/P753S EGFR, ERBB, mENA, ERBB1, EGF-R d747-752/P753S
132 EGFR d752-759 EGFR, ERBB, mENA, ERBB1, EGF-R d752-759
133 EGFR G719C EGFR, ERBB, mENA, ERBB1, EGF-R G719C
134 EGFR G719S EGFR, ERBB, mENA, ERBB1, EGF-R G719S
135 EGFR L718Q EGFR, ERBB, ERBB1, mENA
136 EGFR L858R EGFR, ERBB, ERBB1, EGF-R L858R
137 EGFR L861Q EGFR, ERBB, mENA, ERBB1, EGF-R L861Q
138 EGFR T790M EGFR, ERBB, ERBB1, EGF-R T790M
139 EGFR T790M/C797S/L858R EGFR, ERBB, ERBB1, EGF-R T790M/C797S/L858R
140 EGFR T790M/L858R EGFR, ERBB, ERBB1, EGF-R T790M/L858R
141 EIF2AK2 EIF2AK2, EIF2AK1, PKR, PRKR
142 EIF2AK3 EIF2AK3, DKFZp781H1925, PEK, PERK, WRS
143 EML4 ALK ALK
144 EML4 ALK F1174L ALK
145 EPHA1 EPHA1, EPH, EPHT, EPHT1
146 EPHA2 EPHA2, ECK
147 EPHA3 EPHA3, ETK, ETK1, EphA3, HEKECK, HEK4, TYRO4
148 EPHA4 EPHA4, HEK8, SEK, TYRO1
149 EPHA5 EPHA5, CEK7, EHK1, EphA5, HEK7, Hek7, TYRO4
150 EPHA6 EPHA6, EHK2, EHK-2, EPA6
151 EPHA7 EPHA7, EHK3, HEK11
152 EPHA8 EPHA8, EEK, EphA8, HEK3, KIAA1459
153 EPHB1 EPHB1, ELK, NET, Hek6, EPHT2
154 EPHB2 EPHB2, DRT, ERK, Hek5, EPHT3, Tyro5
155 EPHB3 EPHB3, ETK2, HEK2, TYRO6
156 EPHB4 EPHB4, HTK, MYK1, TYRO11
157 ERBB2 ERBB2, NEU, NGL, HER2, TKR1, HER-2, ERBB2 wt
158 ERBB2 775YVMA776 ERBB2, CD340, HER2, MLN19, NGL, TKR1
159 ERBB4 ERBB4, n/a
160 ERK1 MAPK3, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3
161 ERK2 MAPK1, ERK, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41
162 ERK5 MAPK7, BMK1, ERK4, PRKM7
163 ERK7 MAPK15, ERK8, MAPK15
164 FAK PTK2, FADK, pp125FAK, FAK aa2-1052
165 FAK aa411-686 PTK2, FADK, pp125FAK
166 FER FER, TYK3, c-FER, p94-FER
167 FES FES, FPS
168 FGFR1 FGFR1, H2, H3, H4, H5, CEK, FLG, FLT2, KAL2, BFGFR, C-FGR, N-SAM, FGF-R1 wt
169 FGFR1 V561M FGFR1, FGFR-1, bFGF-R, FLT2, CEK, CD331, FGF-R1 V561M
170 FGFR2 FGFR2, FGFR2, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, FGFR-2, JWS, KGFR, KSAM, K-SAM, TK14, TK25
171 FGFR3 FGFR3, ACH, CD333, CEK2, FGFR-3, HSFGFR3EX, JTK4, FGF-R3 wt
172 FGFR3 G697C FGFR3, ACH, CD333, CEK2, FGFR-3, HSFGFR3EX, JTK4, FGF-R3 G697C
173 FGFR3 K650E FGFR3, ACH, CD333, CEK2, FGFR-3, HSFGFR3EX, JTK4, FGF-R3 K650E
174 FGFR3 K650M FGFR3, ACH, CD333, CEK2, FGFR-3, HSFGFR3EX, JTK4, FGF-R3 K650M
175 FGFR4 FGFR4, TKF, JTK2, MGC20292, FGF-R4
176 FGR FGR, SRC2, c-fgr, p55c-fgr
177 FLT3 FLT3, CD135, FLK2, STK-1, STK1, FLT3 wt
178 FLT3 D835Y FLT3, CD135, FLK2, STK-1, STK1
179 FLT3 ITD FLT3, CD135, FLK2, STK-1, STK1
180 FRK FRK, GTK, PTK5, RAK
181 FYN FYN, SLK, SYN, p59-Fyn, FYN wt
182 FYN Y531F FYN, SLK, SYN, p59-FYN, cFYN
183 GRK2 ADRBK1
184 GRK3 ADRBK2
185 GRK4 GRK4, GPRK2L, GPRK4, GRK4a, IT11
186 GRK5 GRK5
187 GRK6 GRK6
188 GRK7 GRK7
189 GSG2 GSG2, Haspin
190 GSK3alpha GSK3A, GSK3-alpha
191 GSK3beta GSK3B, GSK3-beta
192 HCK HCK, JTK9
193 HIPK1 HIPK1, KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2
194 HIPK2 HIPK2, PRO0593
195 HIPK3 HIPK3, ANPK, DYRK6, FIST, FIST3, PKY, YAK1
196 HIPK4 HIPK4, FLJ32818
197 HRI EIF2AK1, HCR
198 IGF1R IGF1R, JTK13, IGF1-R
199 IKKalpha CHUK, IKBKA, IKK1, IKKA, NFKBIKA, TCF16, IKK-alpha
200 IKKbeta IKBKB, IKK2, IKKB, NFKBIKB, IKK-beta
201 IKKepsilon IKBKE, IKKE, IKKI, IKK-i, KIAA0151, IKK-epsilon
202 INSR INSR, INS-R
203 INSRR INSRR, IRR, INSR-R
204 IRAK1 IRAK1, IRAK, Pelle
205 IRAK4 IRAK4, REN64, NY-REN-64
206 IRAK4 aa104-460 (untagged) IRAK4, REN64, NY-REN-64
207 ITK ITK, EMT 2, LYK 2, PSCTK2 2, IL2-inducible T-cell kinase
208 JAK1 JAK1, JAK1A, JAK1B, JTK3, JAK1 aa583-1154 wt
209 JAK1 aa850-1154 JAK1, JAK-1, JAK1A, AK1B, JAK1 aa850-1154 wt
210 JAK1 S729C JAK1, JAK1A, JAK1B, JTK3, JAK1 aa583-1154 S729C
211 JAK2 JAK2, n/a
212 JAK3 JAK3, JAKL, L-JAK, LJAK
213 JNK1 MAPK8, PRKM8, SAPK1, JNK1-alpha1
214 JNK2 MAPK9, PRKM9, p54aSAPK, JNK2-alpha2
215 JNK3 MAPK10, JNK3A, p54bSAPK
216 KIT KIT, C-Kit, PBT, CD117, SCFR, c-kit, KIT wt
217 KIT A829P KIT, C-Kit, PBT, CD117, SCFR, c-kit
218 KIT D816H KIT, C-Kit, PBT, CD117, SCFR, c-kit
219 KIT D816V KIT, C-Kit, PBT, CD117, SCFR, c-kit
220 KIT T670I KIT, CD117, SCFR, PBT, C-Kit
221 KIT V559D KIT, C-Kit, PBT, CD117, SCFR, c-kit
222 KIT V559D/T670I KIT, C-Kit, PBT, CD117, SCFR, c-kit
223 KIT V559D/V654A KIT, C-Kit, PBT, CD117, SCFR, c-kit
224 KIT V560G KIT, C-Kit, PBT, CD117, SCFR, c-kit
225 KIT V654A KIT, C-Kit, PBT, CD117, SCFR, c-kit
226 LCK LCK, n/a
227 LIMK1 LIMK1, LIMK
228 LIMK2 LIMK2
229 LRRK2 LRRK2, PARK8, ROCO2, FLJ45829, DKFZp434H2111, LRRK2 wt
230 LRRK2 G2019S LRRK2, PARK8, ROCO2, FLJ45829, DKFZp434H2111
231 LRRK2 I2020T LRRK2, PARK8, ROCO2, FLJ45829, DKFZp434H2111
232 LRRK2 R1441C LRRK2, PARK8, ROCO2, FLJ45829, DKFZp434H2111
233 LTK LTK, TYK1
234 LYN LYN, JTK8
235 MAP3K1 MAP3K1, MAPKKK1, MEKK, MEKK1
236 MAP3K10 MAP3K10, MLK2, MST, MEKK10
237 MAP3K11 MAP3K11, MGC17114, MLK-3, PTK1, SPRK
238 MAP3K7/MAP3K7IP1 MAP3K7, TAK1, TGF1a, MEKK7
239 MAP3K9 MAP3K9, MLK1, PRKE1, MEKK9
240 MAP4K2 MAP4K2, BL44, GCK, RAB8IP
241 MAP4K4 MAP4K4, HGK, MEKKK4, NIK
242 MAP4K5 MAP4K5, KHS1, GCKR, KHS, MAPKKKK5
243 MAPKAPK2 MAPKAPK2, n/a
244 MAPKAPK3 MAPKAPK3, 3PK, MAPKAP, MAPKAP3
245 MAPKAPK5 MAPKAPK5, PRAK
246 MARK1 MARK1, KIAA1477
247 MARK2 MARK2, EMK1, MGC99619, PAR-1, ELKL motif kinase 1
248 MARK3 MARK3, CTAK1, KP78, PAR1A
249 MARK4 MARK4, KIAA1860, MARKL1
250 MASTL MASTL, GLW, GREATWALL, GWL, hGWL, MAST-L, THC2
251 MATK MATK, CHK, CTK, DKFZp434N1212, HHYLTK, HYL, Lsk, MGC1708, MGC2101
252 MEK1 MAP2K1, MAPKK1, MKK1, PRKMK1, MEK1 wt
253 MEK1 F53L MAP2K1, MAP2K1, MAPKK1, MAPKK 1, MKK1, PRKMK1
254 MEK1 SESE MAP2K1, MAPKK1, MKK1, PRKMK1, MEK1 S218E/S222E
255 MEK2 MAP2K2, MAPKK2, MKK2, PRKMK2
256 MEK5 MAP2K5, MAP2K5, MAPKK5, MKK5, PRKMK5
257 MEKK2 MAP3K2, MAPKKK2, MEKK2B
258 MEKK3 MAP3K3, MAPKKK3, MEK kinase3
259 MELK MELK, PK38
260 MERTK MERTK, MER, MER-PEN, RP38
261 MET MET, HGFR, RCCP2, MET wt
262 MET D1228H MET, HGFR, RCCP2
263 MET D1228N MET, HGFR, RCCP2
264 MET F1200I MET, HGFR, RCCP2
265 MET G1163R MET, HGFR, RCCP2
266 MET L1195V MET, HGFR, RCCP2
267 MET M1250T MET, HGFR, RCCP2
268 MET Y1230A MET, HGFR, RCCP2
269 MET Y1230C MET, HGFR, RCCP2
270 MET Y1230D MET, HGFR, RCCP2
271 MET Y1230H MET, HGFR, RCCP2
272 MET Y1235D MET, HGFR, RCCP2
273 MINK1 MINK1, B55, YSK2, MAP4K6, ZC3
274 MKK4 MAP2K4, JNKK, JNKK1, MAPKK4, MEK4, PRKMK4, SEK, SERK1
275 MKK6 SDTD MAP2K6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3, MKK6 S207D/T211D
276 MKK7 MAP2K7, MAPKK7, MEK7, PRKMK7
277 MKNK1 MKNK1, MNK1
278 MKNK2 MKNK2, MNK2, GPRK7
279 MLK4 n/a, KIAA1804
280 MST1 STK4, KRS2, YSK3
281 MST2 STK3, MST-2, KRS1
282 MST3 STK24, MST-3, MST3B, STK3
283 MST4 MST4, MASK
284 MTOR FRAP1, FRAP, FRAP2, RAFT1, RAPT1, rapamycin target protein
285 MUSK MUSK, n/a
286 MYLK MYLK, smMLCK, FLJ12216, KRP, MLCK, MLCK108, MLCK210
287 MYLK2 MYLK2, KMLC, MLCK, skMLCK
288 MYLK3 MYLK3, caMLCK, MLCK2, MYLK2
289 NEK1 NEK1, NY-REN-55
290 NEK11 NEK11, FLJ23495
291 NEK2 NEK2, NLK1, HsPK21, HsPK 21
292 NEK3 NEK3, HSPK36, MGC29949
293 NEK4 NEK4, NRK2, STK2
294 NEK6 NEK6, SID6-1512
295 NEK7 NEK7, n/a
296 NEK9 NEK9, DKFZp434D0935, MGC16714, NERCC, NERCC1, Nek8
297 NIK MAP3K14, FTDCR1B, HS, HSNIK
298 NLK NLK, n/a
299 NPM1 ALK n/a, n/a
300 NPM1 ALK F1174L n/a, n/a
301 p38alpha MAPK14, p38-alpha
302 p38beta MAPK11, p38-beta
303 p38delta MAPK13, p38-delta
304 p38gamma MAPK12, ERK-6, ERK3, ERK5, ERK6, PRKM12, SAPK-3, SAPK3, p38-gamma
305 PAK1 PAK1, PAKalpha
306 PAK2 PAK2, PAK65, PAKgamma
307 PAK3 PAK3, CDKN1A, MRX30, OPHN3, PAK3beta, bPAK, hPAK3
308 PAK4 PAK4, n/a
309 PAK6 PAK6, PAK5
310 PAK7 PAK7, KIAA1264, MGC26232
311 PASK PASK, DKFZP434O051, DKFZp686P2031, KIAA0135, PASKIN, STK3
312 PBK PBK, TOPK, SPK, Nori-3, FLJ14385
313 PDGFRalpha PDGFRA, PDGFR2, CD140a, PDGFR-alpha wt
314 PDGFRalpha D842V PDGFRA, PDGFR2, CD140a, PDGFR-alpha D842V
315 PDGFRalpha T674I PDGFRA, PDGFR2, CD140a, PDGFR-alpha T674I
316 PDGFRalpha V561D PDGFRA, PDGFR2, CD140a, PDGFR-alpha V561D
317 PDGFRbeta PDGFRB, JTK12, PDGFR, CD140B, PDGFR1, PDGF-R-beta, PDGFR-beta
318 PDK1 PDPK1, PKB-like
319 PHKG1 PHKG1, PHKg1
320 PHKG2 PHKG2, PHKg2
321 PI4K2A PI4K2A, PI4KII, PIK42A, RP11-548K23.6
322 PI4K2B PI4K2B, PI4KIIB, PI4KII-BETA, PIK42B
323 PI4KB PI4KB, NPIK, pi4K92, PI4K92, PI4Kbeta, PI4KBETA, PI4K-beta, PI4K-BETA, PI4KIIIBETA, PIK4CB
324 PIK3C2A PIK3C2A, CPK, MGC142218, PI3-K-C2A
325 PIK3C2B PIK3C2B, C2-PI3K, PI3K-C2beta
326 PIK3C2G PIK3C2G, PI3K-C2GAMMA, PI3K-C2-gamma
327 PIK3C3 PIK3C3, hVps34, MGC61518, PI3-kinase type 3, PI3K type 3, Vps34, VPS34
328 PIK3CA/PIK3R1 PIK3CA, MGC142161, MGC142163, p110-alpha, PI3K, PI3K-alpha
329 PIK3CB D1067A/PIK3R1 P110BETA, PI3K, PI3KBETA, PI3K-beta, PIK3C1
330 PIK3CB D1067V/PIK3R1 PIK3CB, P110BETA, PI3K, PI3KBETA, PI3K-beta, PIK3C1
331 PIK3CB D1067Y/PIK3R1 P110BETA, PI3K, PI3KBETA, PI3K-beta, PIK3C1
332 PIK3CB E1051K/PIK3R1 PIK3CB, P110BETA, PI3K, PI3KBETA, PI3K-beta, PIK3C1
333 PIK3CB E633K/PIK3R1 PIK3CB, P110BETA, PI3K, PI3KBETA, PI3K-beta, PIK3C1
334 PIK3CB L1049R/PIK3R1 PIK3CB
335 PIK3CB/PIK3R1 PIK3CB, PI3K, PI3KBETA, PI3K-beta, PIK3C1, p110-beta, PIK3CB wt/PIK3R1
336 PIK3CD/PIK3R1 PIK3CD, p110D, P110DELTA, PI3K, PI3K-delta, p110-delta
337 PIK3CG PIK3CG, p120-PI3K, PI3CG, PI3K, PI3Kgamma, PI3K-gamma, p110-gamma
338 PIM1 PIM1, PIM
339 PIM2 PIM2, n/a
340 PIM3 PIM3, n/a
341 PIP5K1A PIP5K1A, PIP5K1-alpha, PIP5KIalpha, PtdIns(4)P-5-kinase 1 alpha
342 PIP5K1B PIP5K1B, MSS4, PIP5K1-beta, STM7
343 PIP5K1C PIP5K1C, PIP5K1-gamma, PIP5Kgamma, PIP5K-GAMMA, PIPKIg_v4
344 PKA PRKACA, MGC48865, PKA
345 PKCalpha PRKCA, PKCA, PRKACA, PKC-alpha
346 PKCbeta1 PRKCB1, PKCB, PRKCB, PRKCB2, MGC41878, PKC-beta, PKC-beta1
347 PKCbeta2 PRKCB1, PKCB, PRKCB, PRKCB2, MGC41878, PKC-beta, PKC-beta2
348 PKCdelta PRKCD, MAY1, MGC49908, nPKC-delta, PKC-delta
349 PKCepsilon PRKCE, PKCE, nPKC-epsilon, PKC-epsilon
350 PKCeta PRKCH, PKC-L, PKCL, PRKCL, nPKC-eta, PKC-eta
351 PKCgamma PRKCG, PKCC, PKCG, SCA14, MGC57564, PKC-gamma
352 PKCiota PRKCI, PKCI, DXS1179E, MGC26534, nPKC-iota, PKC-iota
353 PKCmu PRKD1, PKD, PKCM, PKC-MU, PKC-mu
354 PKCnu PRKD3, EPK2, PKC-nu
355 PKCtheta PRKCQ, PRKCT, nPKC-theta, PKC-theta
356 PKCzeta PRKCZ, PKC2, PKC-zeta
357 PKMYT1 PKMYT1, MYT1
358 PKMzeta PRKCZ, PKM-zeta, nPKC-zeta, PKC2, PKC-zeta wt aa184-592 (PKM-zeta)
359 PKN3 PKN3, PKNbeta, RP11-545E17.1
360 PLK1 PLK1, PLK, STPK13
361 PLK3 PLK3, CNK, FNK, PRK
362 PRK1 PKN1, DBK, PKN, PAK1, PRK1, PRKCL1, MGC46204
363 PRK2 PKN2, PRKCL2, PAK-2
364 PRKD2 PRKD2, PKD2, HSPC187
365 PRKG1 PRKG1, PKG1, CGKI, MGC71944, PGK, PRKG1B, PRKGR1B, cGKIBETA, cGKI-alph
366 PRKG2 PRKG2, PKG2, PRKGR2, cGKII
367 PRKX PRKX, PKX1
368 PYK2 PTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK, CAK beta
369 RAF1 YDYD RAF1, c-RAF, RAF1 Y340D/Y341D (untagged)
370 RET RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1, RET wt
371 RET E762Q RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
372 RET G691S RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
373 RET G810C RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
374 RET G810R RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
375 RET G810S RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
376 RET M918T RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
377 RET R749T RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
378 RET R813Q RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
379 RET S891A RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
380 RET V804E RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
381 RET V804L RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
382 RET V804M RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
383 RET Y791F RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
384 RET Y806H RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
385 RIPK2 RIPK2, CARD3, CARDIAK, CCK, GIG30, RICK, RIP-2, RIP2
386 RIPK4 RIPK4, ANKK2, ANKRD3, DIK, MGC129992, MGC129993, PKK, RIP4
387 RIPK5 DSTYK, SgK496, SHIK
388 ROCK1 ROCK1, P160ROCK
389 ROCK2 ROCK2, KIAA0619, ROC2
390 RON MST1R, CD136, CDw136, PTK8
391 ROS ROS1, MCF3
392 RPS6KA1 RPS6KA1, RSK3, HU-1, MAPKAPK1A, RSK, RSK1
393 RPS6KA2 RPS6KA2, RSK1, HU-2, MAPKAPK1C, RSK, RSK3
394 RPS6KA3 RPS6KA3, HU-2, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2
395 RPS6KA4 RPS6KA4, MSK2, RSK-B
396 RPS6KA5 RPS6KA5, MSK1, EC 2.7.11, MGC1911, MSPK1, RLPK, RSKL
397 RPS6KA6 RPS6KA6, RSK4
398 S6K RPS6KB1, S6K1, STK14A
399 S6Kbeta RPS6KB2, KLS, P70-beta-1, P70-beta-2, S6K-beta2, S6K2, SRK, p70S6Kb, S6K-beta
400 SAK PLK4, SAK, STK18
401 SGK1 SGK, n/a
402 SGK2 SGK2, H-SGK2, dJ138B7.2
403 SGK3 SGKL, CISK, SGK2, SGK3
404 SIK1 SIK1, MSK, SNF1LK, SIK, SIK-1, SNF1LK
405 SIK2 SIK2, QIK, SNF1LK2
406 SIK3 SIK3, L19, QSK, SIK-3
407 SLK SLK, KIAA0204, STK2, bA16H23.1, se20-9
408 SNARK NUAK2, DKFZp434J037
409 SNK PLK2, SNK
410 SRC SRC, ASV, SRC1, c-SRC, p60-Src, SRC (GST-HIS-tag)
411 SRMS SRMS, C20orf148, SRM, dJ697K14.1
412 SRPK1 SRPK1, SFRSK1
413 SRPK2 SRPK2, SFRSK2
414 STK17A STK17A, DRAK1
415 STK23 SRPK3, MSSK1, MGC102944
416 STK25 STK25, DKFZp686J1430, SOK1, YSK1
417 STK33 STK33
418 STK39 STK39, STLK3, DCHT, SPAK
419 SYK SYK, n/a, SYK aa1-635
420 SYK aa356-635 SYK
421 TAOK2 TAOK2, KIAA0881, MAP3K17, PSK, PSK1, TAO1, TAO2
422 TAOK3 TAOK3, DPK, JIK, MAP3K18, TAO kinase 3
423 TBK1 TBK1, CDC37, HSPCA, HSPCB, IKBKG, NAK, T2K, TANK, TRAF2
424 TEC TEC, PSCTK4
425 TGFBR1 TGFBR1, ALK5, ACVRLK4, TGFB-R1
426 TGFBR2 TGFBR2, HNPCC6, MFS2, RIIC, TGFR-2, TGFbeta-RII, TGFB-R2
427 TIE2 TEK, VMCM, TIE-2, VMCM1, CD202B, TIE2 wt
428 TIE2 R849W TEK, VMCM, TIE-2, VMCM1, CD202B
429 TIE2 Y1108F TEK, VMCM, TIE-2, VMCM1, CD202B
430 TIE2 Y897S TEK, VMCM, TIE-2, VMCM1, CD202B
431 TLK1 TLK1, PKU-beta, KIAA0137
432 TLK2 TLK2, MGC44450, PKU-ALPHA
433 TNK1 TNK1, n/a
434 TRKA NTRK1, MTC, TRK, TRK1, TRKA, TRK-A wt
435 TRKA G667C MTC, TRK1, TRKA, TRK-A G667C
436 TRKB NTRK2, GP145-TrkB, TRKB, Trk-B, TRK-B
437 TRKC NTRK3, GP145-TrkC, TRKC, Trk-C, TRK-C
438 TSF1 STK16, KRCT, MPSK, PKL12
439 TSK2 TSSK2, DGS-G, SPOGA2, FLJ38613
440 TSSK1 TSSK1, FKSG81, SPOGA4, STK22D
441 TTBK1 TTBK1, BDTK, TTBK1 aa1-1321
442 TTBK1 aa1-480 TTBK1, BDTK
443 TTBK2 TTBK2, BDTK, KIAA1855, RP3-330M21.4
444 TTK TTK, ESK, MPS1L1, PYT
445 TXK TXK, BTKL, PSCTK5, PTK4, RLK
446 TYK2 TYK2, JTK1
447 TYRO3 TYRO3, BYK, Brt, Dtk, Sky, Tif
448 ULK2 ULK2, ATG1B, KIAA0623, Unc51.2
449 VEGFR1 FLT1, FLT, VEGF-R1
450 VEGFR2 KDR, FLK1, VEGFR, VEGF-R2
451 VEGFR3 FLT4, PCL, VEGF-R3
452 VRK1 VRK1, n/a
453 VRK2 VRK2, n/a
454 WEE1 WEE1, WEE1hu
455 WNK1 WNK1, KDP, KIAA0344, PHA2C, PRKWNK1
456 WNK2 WNK2, KIAA1760, NY-CO-43, P/OKcl.13, PRKWNK2, SDCCAG43
457 WNK3 WNK3, KIAA1566, PRKWNK3
458 YES YES, C-YES, HsT441, P61-YES
459 ZAK MLTK, mlklak, AZK
460 ZAP70 ZAP70, SRK, STD, TZK, ZAP-70
EXCEL

Info in Brief

Kinase Panel

460 kinases, including 94 disease-relevant kinase
mutants and 20 lipid kinases

Assay Technologies

Protein kinases: FlashPlate™-based radiometric assay;
lipid kinases: ADP-Glo™ assay technology (Promega)

ATP conc

App. ATP-Km for each kinase

Testing Modes

Single concentration measurement or IC50 profiling
(10 conc in semi-log steps)

Cpd Submission

100 x Stock solution in 100% DMSO or
pre-weighed powder (request guidelines)

Report

Detailed report for each project
Sample report will be provided upon request

Turnaround Time

No fixed time slots; first come - first served;
routinely within 10 working days

Info Sheets

Method: Radiometric Assay, Method: ATP-Glo™ Assay

Guidelines for Cpd Submission

Guidelines       SPF       CSF