Biochemical Assay Services

Custom-Tailored Biochemical Assay Services

Field of Application

Custom-tailored biochemical assay services can be used to address specific questions of customers by using ProQinase’s comprehensive experience in the field of biochemical kinase assays.

Our Service

Typical Examples of Custom-Tailored Projects

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Kind of Service

Purpose of the Service

Info Sheet

1

Biochemical ATP-Competition Assay

To provide information whether a test cpd shows an ATP competitive mode of action

2

Kinase Activation Assays

To develop kinase cascade activity assays which include activation steps for one or two kinases, e.g. for MAPK cascades

Infos in Brief

Assay Technology

Radiometric FlashPlateTM Assay

Principle of ATP-Competition Assay

IC50 of test cpd is determined at 5 different ATP conc

Example of ATP-Competition Assay

ProQinase Poster from AACR meeting 2017, Washington

Available Tools for Activation Assays

32 Proteins of different activation status from various MAPK cascades & many other protein kinases

Example of Kinase Activation Assay

ProQinase Poster from EORTC-NCI-AACR Symposium, Nov. 6-9, 2012, Dublin