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ProQinase has established a large panel of in
vivo tumor models with focus on clinical relevance.
Spheroid-Based in vivo Angiogenesis Assay
This assay is an innovative method to evaluate test compounds which are
directed against a human, endothelial cell specific target.
Orthotopic
Tumor Models
ProQinase offers orthotopic and metastasizing in vivo tumor models in mice.
The growth of the orthotopically implanted tumors and the antimetastatic potency of test compounds can be monitored in vivo
taking advantage of a bioluminescence imaging system.
Subcutaneous Xenograft
Tumor Models
ProQinase offers subcutaneous xenograft tumor models in mice.
Target-specific
Tumor Models with Genetically Engineered Cells
ProQinase offers target-specific tumor models in mice using cell lines, which were
genetically engineered to control the expression of tumor-relevant proteins.
Study Design and Readouts
ProQinase provides customized protocols and besides standard readouts also in vivo imaging (bioluminescence and ultrasound).
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