Several cell models are available that allow the analysis of the effect of a test compound on substrate phosphorylation in intact cells.

Cellular phosphorylation ELISAs are available for

• AKT1
• Aurora-B
• B-RAF-VE
  
• EGF-R
• EPHB4
• ERBB2
  
• FLT3-wt
• IGF1-R
• KIT
• PDGFR-beta
• TIE2
• VEGF-R2

We offer cellular IC50 determination (9 concentrations, half-logarithmic) for compounds at the level of protein phosphorylation in cells. Detailed descriptions of the assays are available on request, please send us an e-mail.

Additional cellular kinase assays are under development.

Please ask for our guidelines for information how to provide your test compounds for cellular testing.