ProQinase Tools & Tests
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iProKiTe®-Package 1: Recombinant Protein Kinases & Substrates

Currently, 140 recombinant, catalytically active protein kinases and some substrates are available:

All Kinases
Serine/Threonine Kinases
Receptor Tyrosine Kinases
Cytoplasmic Tyrosine Kinases
Recombinant Substrates For Kinases
Additional Kinases Only For Screening and Profiling

Serine/Threonine Kinases
Kinase: a data sheet describing the kinase or the cofactor can be obtained by clicking on its name

A B C D G I J M N P R S T V

No. Kinase Product Number Produt description HGNC name Synonyms
           
1 ACV-R1 0372-0000-1 human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells ACVR1 ACTRI; ACVRLK2; ALK2; SKR1
2 AKT1 0132-0000-2 human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells AKT1 PKB; RAC; PRKBA; RAC-ALPHA
3 AKT2 0276-0000-2 human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells AKT2 PRKBB; PKBBETA; RAC-BETA
4 AKT3 0436-0000-2 human, C-terminal fragment, GST-HIS fusion protein, activated, expressed in Sf9 cells AKT3 PKBG; PRKBG; STK-2; RAC-gamma; RAC-PK-gamma
5 AMPK-alpha1 tr 0383-0000-1 human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells PRKAA1 MGC33776; MGC57364
6 AMPK-alpha1 fl 0289-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PRKAA1 MGC33776; MGC57364
7 ARK5 0300-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells NUAK1 KIAA0537
8 Aurora-A 0166-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells STK6 AIK; ARK1; AURA; BTAK; STK15; MGC34538
9 Aurora-B 0190-0000-1 human, full-length, GST-HIS fusion protein, expressed in Sf9 cells AURKB AIK2; AIM1; ARK2; AurB; IPL1; STK5; AIM-1; STK12
10 Aurora-C 0315-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells AURKC AIE2; AIK3; STK13
11 B-RAF wt 0403-0000-1 human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells BRAF B-Raf; B-raf-1; BRAF1; RAFB1
12 B-RAF VE 0404-0000-1 human, C-terminal fragment, mutationally activated (V600E), GST-HIS fusion protein, expressed in Sf9 cells BRAF B-Raf; B-raf-1; BRAF1; RAFB1
13 CDC42BPB 0382-0000-1 human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells CDC42BPB MRCK-beta; MRCKb
14 CDK1/CycB1 0134-0135-1 human, full length, GST-HIS fusion proteins, expressed in Sf9 cells CDC2 p34
15 CDK1/CycE 0134-0055-1 human, full length, GST-HIS fusion proteins, expressed in Sf9 cells CDC2 p34
16 CDK2/CycA 0050-0054-1 human, full length, GST-HIS fusion proteins, expressed in Sf9 cells CDK2 p33(CDK2)
17 CDK2/CycE 0050-0055-1 human, full length, GST-HIS fusion proteins, expressed in Sf9 cells CDK2 p33(CDK2)
18 CDK3/CycE 0212-0055-1 human, full length, GST-HIS fusion proteins, expressed in Sf9 cells CDK3 n/a
19 CDK4/CycD1 0142-0143-1 human, full length, GST-HIS fusion proteins, expressed in Sf9 cells CDK4 CMM3; PSK-J3; MGC14458
20 CDK4/CycD3 0142-0373-1 human, full length, CDK4: GST-HIS fusion protein, CycD3: HIS-tagged protein, expressed in Sf9 cells CDK4 CMM3; PSK-J3; MGC14458
21 CDK5/p25NCK 0356-0389-1 human, full length, CDK5: GST-HIS fusion protein, p25NCK: HIS-tagged protein, expressed in Sf9 cells CDK5 PSSALRE
22 CDK5/p35NCK 0356-0355-1 human, full length, CDK5: GST-HIS fusion protein, p35NCK: HIS-tagged protein, expressed in Sf9 cells CDK5 PSSALRE
23 CDK6/CycD1 0051-0143-1 human, full length, GST-HIS fusion proteins, expressed in Sf9 cells CDK6 PLSTIRE; MGC59692
24 CDK7/CycH/MAT1 0366-0360-4 human, full length, CDK7: GST-HIS fusion protein, CycH/MAT1: HIS-tagged proteins, expressed in Sf9 cells CDK7 CAK1; CDKN7; STK1; p39MO15
25 CDK8/CycC 0376-0390-1 human, full length, CDK8: GST-HIS fusion protein, CycC: HIS-tagged protein, expressed in Sf9 cells CDK8 K35
26 CDK9/CycT 0371-0345-1 human, full length, CDK9: GST-HIS fusion protein, CycT: HIS-tagged protein, expressed in Sf9 cells CDK9 C-2k; CDC2L4K35; PITALRE; TAK
27 CHK1 0282-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells CHEK1 n/a
28 CK1-alpha1 0406-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells CSNK1A1 CK1; HLCDGP1; PRO2975
29 CK2-alpha1 0124-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells CSNK2A1 CKII; CK2A1
30 CK2-alpha2 0412-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells CSNK2A2 n/a
31 CLK1 0447-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells CLK1 CLK; CLK/STY
32 COT 0180-0000-1 human, internal fragment, GST-HIS fusion protein, expressed in Sf9 cells MAP3K8 EST; ESTF; TPL2; Tpl-2; c-COT
33 DAPK1 0332-0000-1 human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells DAPK1 n/a
34 GSK3-beta 0310-0000-1 human, full length,GST-HIS fusion protein, expressed in Sf9 cells GSK3B n/a
35 IKK-beta 0258-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells IKBKB IKK2; IKKB; NFKBIKB
36 IKK-epsilon 0320-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells IKBKE IKKE; IKKI; IKK-i; KIAA0151
37 IRAK4 0268-0000-1 human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells IRAK4 REN64; NY-REN-64
38 JNK1 0419-0000-1 human, full length, HIS-tagged protein, expressed in Sf9 cells MAPK8 JNK; JNK1A2; JNK21B1/2; PRKM8; SAPK1
39 JNK3 0214-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells MAPK10 JNK3A; PRKM10; p493F12; FLJ12099; p54bSAPK
40 MAPKAPK5 0380-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells MAPKAPK5 PRAK
41 MARK1 0432-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells MARK1 KIAA1477
42 MARK3 0433-0000-1 human, full length, GST-HIS fusionprotein, expressed in Sf9 cells MARK3 CTAK1; KP78; PAR1A
43 MEK1 SESE 0385-0000-1 human, full length, mutationally activated (S218E, S222E), GST-HIS fusion protein, expressed in Sf9 cells MAP2K1 MAPKK1; MKK1; PRKMK1
44 MKK6 SDTD 0396-0000-1 human, full length, mutationally activated (S207D, T211D), GST-HIS fusion protein, expressed in Sf9 cells MAP2K6 MAPKK6; MEK6; MKK6; PRKMK6; SAPKK3
45 MST4 0286-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells MST4 MASK
46 MYLK2 0445-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells MYLK2 KMLC; MLCK
47 NEK2 0290-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells NEK2 NLK1; HsPK21; HsPK 21
48 NEK6 0209-0000-1 human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells NEK6 SID6-1512
49 NIK 0344-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells MAP3K14 FTDCR1B; HS; HSNIK
50 NLK 0253-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells NLK n/a
51 p38-alpha 0443-0000-3 human, full length, activated, untagged, expressed in E.coli MAPK14 p38-alpha
52 p38-beta 0455-0000-3 human, full length, activated, untagged, expressed in E.coli MAPK11 p38-beta
53 PAK1 0357-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PAK1 PAKalpha
54 PAK2 0304-0000-1 human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells PAK2 PAK65; PAKgamma
55 PAK3 0422-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PAK3 CDKN1A; MRX30; OPHN3; PAK3beta; bPAK; hPAK3
56 PAK4 0365-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PAK4 n/a
57 PAK6 0423-0000-1 human, full length, GST-HIS fusionprotein, expressed in Sf9 cells PAK6 PAK5
58 PAK7 0410-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PAK7 KIAA1264; MGC26232

59

PBK 0185-0000-2 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PBK TOPK; SPK; Nori-3; FLJ14385
60 PCTAIRE1 0189-0000-1 human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells PCTK1 PCTAIRE; PCTGAIRE
61 PDK1 0353-0000-1 human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells PDPK1 PkB kinase; MGC20087; MGC35290; PRO0461
62 PIM1 0186-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PIM1 PIM
63 PIM2 0223-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PIM2 n/a
64 PKC-alpha 0222-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PRKCA PKCA; PRKACA; PKC-alpha
65 PKC-beta1 0067-0000-1 human, full length, GST fusion protein, expressed in Sf9 cells PRKCB1 PKCB; PRKCB; PRKCB2; MGC41878; PKC-beta
66 PKC-beta2 0116-0000-1 human, full length, GST fusion protein, expressed in Sf9 cells PRKCB1 PKCB; PRKCB; PRKCB2; MGC41878; PKC-beta
67 PKC-delta 0232-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PRKCD MAY1; MGC49908; nPKC-delta
68 PKC-epsilon 0203-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PRKCE PKCE; nPKC-epsilon
69 PKC-eta 0061-0000-1 mouse, full length, GST-HIS fusion protein, expressed in Sf9 cells PRKCH PKCL; PKC-L; PRKCL; MGC5363; MGC26269; nPKC-eta
70 PKC-gamma 0204-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PRKCG PKCC; PKCG; SCA14; MGC57564
71 PKC-iota 0114-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PRKCI PKCI; DXS1179E; MGC26534; nPKC-iota
72 PKC-mu 0115-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PRKD1 PKD; PKCM; PKC-MU
73 PKC-theta 0113-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PRKCQ PRKCT; nPKC-theta
74 PKC-zeta 0117-0000-1 human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells PRKCZ PKC2
75 PLK1 0183-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PLK1 PLK; STPK13
76 PLK3 0437-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PLK3 CNK; FNK; PRK
77 PRK1 0207-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PKN1 DBK; PKN; PAK1; PRK1; PRKCL1; MGC46204
78 ROCK2 0347-0000-1 human, internal fragment, GST-HIS fusion protein, expressed in Sf9 cells ROCK2 KIAA0619; ROC2
79 S6K 0318-0000-2 human, N-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells RPS6KB1 S6K1; STK14A
80 SAK 0306-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PLK4 SAK; STK18
81 SGK1 0199-0000-2 human, full length, activated, GST fusion protein, expressed in Sf9 cells SGK n/a
82 SGK3 0198-0000-2 human, full length, activated, GST fusion protein, expressed in Sf9 cells SGKL CISK; SGK2; SGK3
83 SNARK 0414-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells NUAK2 DKFZp434J037
84 SNK 0277-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells PLK2 SNK
85 SRPK1 0434-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells SRPK1 SFRSK1
86 SRPK2 0381-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells SRPK2 SFRSK2
87 TGFB-R1 0397-0000-1 human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells TGFBR1 ALK5; ACVRLK4
88 TSF1 0187-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells STK16 KRCT; MPSK; PKL12
89 TSK2 0220-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells TSSK2 DGS-G; SPOGA2; FLJ38613
90 TTK 0284-0000-1 human, full length,GST-HIS fusion protein, expressed in Sf9 cells TTK ESK; MPS1L1; PYT
91 VRK1 0302-0000-1 human, full length, GST-HIS fusion protein, expressed in Sf9 cells VRK1 n/a


A
B C D G I J M N P R S T V

All Protein Kinases in these lists are prepared in large lots (>20 mg) and only released after thorough validation to guarantee our customers a continuous supply of uniform enzymes. If you search for a kinase with an alternative name, please check our list of the kinome. To get more information about the available lots, please request a data sheet by sending us a short e-mail.

*Sale and use of this product are limited by license. More detailed information can be found on kinase specific data sheets, which are available by clicking on the kinase name or on request from ProQinase.

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