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EU-FP6 Programme http://www.proteinkinase-research.org/index.htm: homepage of the EU project "Protein Kinases Novel Drug Targets of Post Genomic Era"
Protein Kinases
http://pkr.genomics.purdue.edu/pkr/Welcome.do: The Protein Kinase Resource is a good starting point and contains basic information about most kinases as well as a lot of very useful links to other resources on the web. Mammalian Phosphorylation Resource: http://mpr.nci.nih.gov/mpr http://www.cellsignal.com/protein_classes/index.html: CST's website provides a lot of graphical information about kinase signalling pathways as well as for the complete human kinome. http://www.genome.jp/kegg/pathway.html: The kegg pathway database contains graphical information about the function of most proteins including kinases.
General Links
http://www.genenames.org: Homepage of the HUGO gene nomenclature committee. Provides information about "official" Gene and Protein designations.
A vast collection of useful tools and information can be found at ExPASy (http://www.expasy.org/). Protein Reviews on the Web: http://mpr.nci.nih.gov/prow/ http://www.ncbi.nlm.nih.gov: The most comprehensive collection of sequence based information, especially usefull is Entrez Gene and OMIM. GeneCards® (http://bioinfo.weizmann.ac.il/cards/index.shtml) is a database of human genes, their products and their involvement in diseases. It offers concise information about the functions of all human genes that have an approved symbol, as well as selected others. www.imagenes-bio.de: imaGenes is developer, producer and distributor of products and services for functional genome research as well as integration platform for genome data.
Partner Companies
4SC AG, Martinsried, Germany
www.4sc.de
4SC develops innovative drug candidates in blockbuster indications such as cancer and autoimmune diseases. 4SC and ProQinase have a long standing collaboration to develop kinase inhibitors for cancer treatment. CRELUX GmbH, Martinsried, Germany
www.crelux.de
Crelux offers x-ray crystallography services and ultra pure protein. Together with ProQinase a joint crystal-grade kinase protein and structures platform is available. PRESTWICK CHEMICAL, Illkirch, France
www.prestwickchemical.com
Prestwick Chemical is a medicinal chemistry company which supports its partners in hit and lead optimization. ChemCon GmbH, Freiburg, Germany
www.chemical-services.de
ChemCon is a service provider for commercial production of APIs, specializing on small molecules.
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