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	Clinical Biomarker Analysis

Clinical Biomarker Analysis Service

ProQinase has established several biomarker assays to determine various biomarker proteins in serum or plasma samples derived from clinical trials. This service includes support for the design of study protocols, the selection of suitable biomarkers and the scheduling of sample collection. We also provide advice regarding sample processing and logistics.

Plasma and serum biomarkers are quantified in clinical trial samples by means of sandwich ELISAs. The focus of ProQinase's Clinical Biomarker Analysis Service is on biomarker proteins which are related to angiogenesis. These biomarker assays complement ProQinase's expertise in the angiogenesis research area.

A biomarker assay is available for the following serum or plasma biomarker proteins:

Biomarker	Type of Biomarker	Prefered Sample Type
Biomarker	Type of Biomarker	Serum	EDTA/Platelet- poor Plasma
ANG1	Ligand	-	X
ANG2	Ligand	X	X
bFGF	Ligand	-	X
HGF	Ligand	X	X
IL-8	Ligand	X	-
PlGF	Ligand	X	X
VEGF-A	Ligand	-	X
VEGF-C	Ligand	-	X
sEGFR	soluble receptor domain	X	X
sE-Selectin	soluble receptor domain	X	-
sSCFR/c-KIT	soluble receptor domain	-	X
sTIE2	soluble receptor domain	X	-
sVEGF-R1	soluble receptor domain	X	X
sVEGF-R2	soluble receptor domain	X	X
sVEGF-R3	soluble receptor domain	X	X

Additional biomarker assays are available on request (including mouse biomarkers).

Please inquire for more specific information about our clinical biomarker service and for the collection & processing guidelines of serum and plasma samples.