Custom tailored in vitro Kinase Assay Services
ProQinase offers completely flexible custom-tailored in vitro kinase assay services. For each project you may freely choose (i) the number of test compounds, (ii) the kinase panel and (iii) the number of datapoints for each test compound (i.e. concentrations and number of replicates). Typical services are broad kinase profiling projects with a few compounds, as well as high throughput screening of large compound libraries (HTS). ProQinase's kinase panel for in vitro testing currently comprises 320 protein kinases. Compound profiling can be performed either as single concentration measurement or as IC50 profiling (10 conc. in semilog steps).
The following important points are common to all custom-tailored in vitro kinase assay service projects:
- Gold standard assay technology: Radiometric 33PanQinaseŽ Assay (using 96- or 384-well FlashPlatesTM)
- Broad kinase panel: 320 protein kinases are available for high throughput screening and compound profiling
- High flexibility: Free choice of kinases, cmpd numbers and datapoints/cmpd for each project
- High reproducibility: All in vitro kinase assays are carried out by robotic systems
- Rapid turnover: No fixed time slots; first come / first serve basis
- Expertise: Our in vitro assay experts are working in the kinase assay field for over 15 years
Examples for custom tailored projects
List of available Kinases for in vitro Kinase Assay Services
Standardized Service Packages
In addition to flexible custom-tailored projects ProQinase offers the ProQinase WholePanelProfiler that allows to generate inhibition profiles of your compounds on the whole protein kinase panel of ProQinase (currently 320) for a very competitive price.
The KinaseFinder as a standardized service package that allows to identify protein kinases that phosphorylate your protein or peptide of interest. This service is currently offered with either 190 Ser/Thr protein kinases or 81 Tyr protein kinases or both.
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