Free Choice Kinase Assay Projects

ProQinase offers completely flexible free choice biochemical kinase assay services. For each project you may freely choose (i) the number of test compounds, (ii) the kinase panel and (iii) the number of data points for each test compound (i.e. concentrations and number of replicates). Typical services are broad kinase profiling projects with a few compounds, as well as high throughput screening of large compound libraries (HTS).

Kinase panel for free choice biochemical kinase assay services

• 358 Protein kinases (including 65 mutant protein kinases)
• 7 Lipid kinases 

Assay technologies

• Protein kinases: radiometric ³³PanQinaseŽ assay
• Lipid kinases: ADP-Glo^TM kinase assay (Promega)

Test mode 

• Single concentration measurement or
• IC50 Profiling (10 conc. in semi-log steps)

The following important points are common to all free choice biochemical kinase assay service projects: 

• Testing at app. ATP Km: With a few exceptions each kinase will be tested at the respective app. ATP Km
• High flexibility: Free choice of kinases, cpd numbers and data points/cpd for each project
• High reproducibility: All biochemical kinase assays are carried out by robotic systems
• Rapid turnover: No fixed time slots; first come / first served basis
• Expertise: Our biochemical assay experts are working in the kinase assay field for over 15 years

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