In vitro Kinase Assay Services 

ProQinase offers completely flexible in vitro kinase assay services. For each project you may freely choose (i) the number of test compounds, (ii) the kinase panel and (iii) the number of datapoints for each test compound (i.e. concentrations and number of replicates). Typical services are broad kinase profiling projects with a few compounds, as well as high throughput screening of large compound libraries (HTS). ProQinase's kinase panel for in vitro testing currently comprises 255 protein kinases. Compound profiling can be performed either as single concentration measurement or as IC50 profiling (10 conc. in semilog steps).

The following features characterize our in vitro kinase assay services:

  • Gold standard assay technology: Radiometric in vitro kinase assay (96- or 384-well FlashPlatesTM)
  • Broad kinase panel: 255 protein kinases are available for high throughput screening and compound profiling
  • High flexibility: Free choice of kinases, cpmd numbers and datapoints/cpmd for each project
  • High reproducibility: All in vitro kinase assays are carried out by robotic systems
  • Rapid turnover: No fixed time slots; first come / first serve basis
  • Expertise: Our in vitro assay experts are working in the kinase assay field for over 15 years
 
 
 

 


 
in vitro testing, kinase profiling, compound profiling, IC50 profiling, high throughput screening
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