Biochemical Assay Services

Free Choice Kinase Assay Projects Kinase Wildtype-Profiler & Kinase 400-Profiler
Kinase MutantProfiler KinaseFinder
Kinase SubstrateFinder HitDetector
 Custom-Tailored Biochemical Assay Services  

 Free Choice Kinase Assay Projects

ProQinase’s biochemical free choice service for kinase activity assays is highly flexible addressing your needs on kinase screening. For each kinase screening you may freely choose (i) the number of test compounds, (ii) the kinase panel (out of currently 371 active protein kinases and 13 lipid kinases) and (iii) the number of data points for each test compound (i.e. concentrations and number of replicates) in this kinase activity assay service.

 

 Kinase Wildtype-Profiler & Kinase 400-Profiler

The Kinase Wildtype-Profiler is a standardized service package which allows kinase profiling of your test samples against a panel of 300 wildtype protein kinases. The 400-Profiler is an even more comprehensive standardized profiling service package including 70 disease-relevant protein kinase mutants and 13 lipid kinases.

 
 Kinase MutantProfiler

With our 6 standardized service packages Kinase MutantProfiler IC50 values will be determined for your compounds by testing the sample at 10 different concentrations in a kinase activity assay against the wild type form and various mutants of the corresponding kinase. These service packages of kinase activity assays are available for ABL1, ALK, EGF-R, KIT, MET and RET.

 
 KinaseFinder

The KinaseFinder is a standardized service package which allows to find out whether your protein or peptide of interest can function as a substrate in a kinase activity assay performed with a broad panel of protein kinases. This kinase screening is currently offered as a Ser/Thr version or a Tyr kinase version.

 
 Kinase SubstrateFinder

ProQinase offers its standardized service Kinase SubstrateFinder in 5 different versions. Each service package comprises a number of potential Ser/Thr or Tyr kinases substrates.
The service allows to identify physiological kinase substrates or substrates which are suitable for biochemical kinase activity assays.


 HitDetector

The HitDetector is a biochemical service package which provides you with a starting point for your protein kinase drug discovery project. The service comprises testing of a small molecule library (25,000 cpds) against a protein kinase of your choice.

 
 Custom-Tailored Biochemical Assay Services
ProQinase offers custom-tailored biochemical assay services according to your individual requirements.

More information about all of our services are available on request.
 

 
kinase profiling, kinase screening, kinase activity assay
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